Why You Need Insulin. People with type 2 diabetes may require insulin when their meal plan, weight loss, exercise and antidiabetic drugs do not achieve targeted blood glucose (sugar) levels. Making them ideal when you are going to travel to hot or super cold climates.

But even in the absence of high glucose. To increase the blood levels of glucose, insulin also increases the activity of the enzyme in the bloodstream. Central to this potentially massive change in metabolism is the development of insulin resistance.